Brief Resolved Unexplained Events (BRUE) Criteria for Infants

PediatricsBeta toolThis tool is in beta. It has undergone internal validation but still requires additional testing. Always confirm the data entered and the results obtained before clinical use. It should not be used as the sole basis for clinical decisions.

Chronologic age

days

Gestational age at birth

weeks

Postconceptional age at event

weeks

Event duration

seconds

Observed qualifying features

Cyanosis or pallorAbsent, decreased, or irregular breathingMarked change in toneAltered responsiveness

Event was sudden

YesNo

Returned to baseline with normal vital signs and appearance

YesNo

Explanation identified after history and examination

YesNo

First event with no prior or clustered events

YesNo

CPR by trained medical provider

YesNo

Concerning history or physical examination findings

YesNo

Enter the data

The result appears automatically once all required fields are complete.

Clinical noticeThis clinical tool supports decision-making and does not replace individual medical assessment.

Context and use

BRUE classification: the event must be sudden, last less than 60 seconds, include at least one qualifying feature, resolve back to baseline, and have no explanation identified after evaluation.

Lower risk: age >60 days, gestational age ≥32 weeks, postconceptional age ≥45 weeks, first event, no CPR by a trained provider, and no concerning history or examination.