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Friedewald LDL

Lipid managementLaboratory medicineCardiovascular preventionBeta toolThis tool is in beta. It has undergone internal validation but still requires additional testing. Always confirm the data entered and the results obtained before clinical use. It should not be used as the sole basis for clinical decisions.

Friedewald is unavailable at triglycerides ≥ 400 mg/dL or ≥ 4.5 mmol/L.

Clinical noticeEducational estimator only. Confirm the result clinically and use a direct or alternative method when Friedewald is out of scope or likely unreliable.

Context and use

Method

Normalize cholesterol and triglycerides to mg/dL; LDL-C = total cholesterol - HDL-C - (triglycerides / 5).

Conversion

Cholesterol: mmol/L × 38.67; triglycerides: mmol/L × 88.57. The result returns in the total-cholesterol unit.

Block if triglycerides ≥ 400 mg/dL or ≥ 4.5 mmol/L. Warn if calculated LDL-C < 70 mg/dL or < 1.8 mmol/L.

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